Microfluidic Devices: Precision Molded Silicone Gaskets for Lab-on-a-Chip.
Microfluidic Devices: Precision Molded Silicone Gaskets for Lab-on-a-Chip.
RubberQ Engineering

Microfluidic Devices: Precision Molded Silicone Gaskets for Lab-on-a-Chip
Problem Statement
Microfluidic devices require silicone gaskets that maintain sealing integrity under repeated thermal cycling (up to 150°C) and exposure to aggressive solvents (e.g., DMSO, acetone). Compression set failure and chemical swelling degrade performance over time.
Material Science Analysis
Standard silicone elastomers (VMQ) fail due to low crosslink density and inadequate filler dispersion. High-performance liquid silicone rubber (LSR) succeeds due to its optimized polymer backbone and platinum-cure system. LSR offers superior thermal stability and chemical resistance, minimizing swelling and compression set.
Technical Specs
- Material: LSR (Liquid Silicone Rubber)
- Shore A Hardness: 50 ± 2
- Tensile Strength: 10 MPa
- Elongation at Break: 500%
- Temperature Range: -50°C to 200°C
- Compression Set: ≤ 10% (22 hrs @ 150°C)
- Chemical Resistance: Resistant to DMSO, acetone, and IPA
Technical Comparison
| Parameter | LSR | VMQ | FKM |
|---|---|---|---|
| Temperature Range (°C) | -50 to 200 | -60 to 180 | -20 to 200 |
| Compression Set (%) | ≤ 10 | ≤ 25 | ≤ 15 |
| Chemical Resistance | Excellent | Good | Excellent |
| Elongation at Break (%) | 500 | 400 | 200 |
Standard Compliance
RubberQ's IATF 16949-certified process ensures batch-to-batch consistency. Our compounding adheres to ASTM D2000 for material callouts and ISO 3601 for sealing performance. Surface preparation and bonding meet ASTM D429 standards.
For custom material compound development or IATF 16949 documentation, consult RubberQ's engineering department.
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